Medical Xpress
Liquid biopsy predicts response to breast cancer immunotherapy
Researchers at Vanderbilt-Ingram Cancer Center have found that liquid biopsies — repeated blood draws taken during treatment — can track and predict how a patient's immune system responds to breast cancer immunotherapy. The discovery addresses a critical gap, as immunotherapy remains inconsistent in shrinking early-stage tumors despite its widespread use. Identifying reliable biomarkers through this non-invasive method could enable clinicians to adjust treatment strategies in real time, potentially improving outcomes for high-risk patients.
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Blocking a cellular inflammation process could result in effective therapy for pancreatic cancer
Researchers have identified a critical weakness in pancreatic cancer cells: defective mitochondria that trigger an inflammatory process tumors rely on to grow. Scientists from The Wistar Institute and ChristianaCare's Helen F. Graham Cancer Center found that blocking this inflammation pathway effectively starves cancer cells of a key survival mechanism. The discovery, published in PNAS, opens a promising new therapeutic avenue for one of oncology's most treatment-resistant diseases.
Read article →Guardian Health
US ‘drowning in misinformation’ under RFK Jr, autism advocates say
Robert F. Kennedy Jr. and other Trump administration health officials are fueling a "crisis of public trust" by spreading misinformation about autism and vaccines, according to a new report from advocacy groups. The report calls on Congress to launch oversight hearings and consider impeachment proceedings against Kennedy and other HHS leaders. Experts warn the administration's messaging over the past year has left the public increasingly unable to distinguish established science from debunked claims.
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The Guardian view on unhealthy Britain: from housing to junk food, there are solutions | Editorial
Britain is getting sicker, younger. New analysis from the Health Foundation reveals healthy life expectancy has fallen over the past two years, meaning people are now living with illness or disability at an earlier age than they were a decade ago — a damning finding for one of the world's wealthiest nations. The Guardian argues that systemic issues from housing to junk food are driving the decline, and that proven solutions exist if policymakers choose to act.
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Scientists cautiously suggest GLP-1s are safe to use around pregnancy
GLP-1 drugs like Ozempic do not appear to increase the risk of major birth defects when taken around pregnancy, according to the most comprehensive study on the subject to date. Researchers at the University of St Andrews analyzed more than 49,000 pregnancies across 20 years in what is now the largest systematic review of GLP-1 exposure during pregnancy. The findings, published in the American Journal of Obstetrics and Gynaecology, offer meaningful reassurance as the drugs become increasingly widespread among women of childbearing age.
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