ScienceDaily
New "super antibiotic" stops deadly gut infection without destroying the microbiome
C. difficile infects half a million Americans annually and stubbornly recurs in roughly one in six patients — largely because standard antibiotics gut the very microbial defenses that keep it at bay. A new compound called EVG7 clears the infection in mice at remarkably low doses while leaving beneficial bacteria intact. If the results translate to humans, it could mark a significant shift in how one of medicine's most persistent superbugs is treated.
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Scientists turn brain cells into Alzheimer’s plaque cleaners
Researchers have reprogrammed astrocytes — the brain's abundant support cells — to actively seek out and clear the amyloid plaques central to Alzheimer's disease, borrowing the CAR technology already proven in cancer treatment. Unlike current therapies that require repeated antibody infusions, this one-time genetic intervention could offer a more durable and targeted solution. If the approach translates to humans, it may represent a fundamental shift in how the disease is treated.
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